Interestingly, the extended PMCA yielded novel forms of misfolded prions that caused new disease phenotypes. When injected into wild-type hamsters, the PMCA-generated hampster PrP Sc caused ...

A system for the rapid amplification of misfolded prion oligomers provides new evidence supporting the prion hypothesis and may offer a powerful diagnostic tool. The prion hypothesis remains ...

Luckily for us, ice-nine is fictitious. But its biological counterpart, unfortunately, is not. The misfolded proteins known as prions are very real. Prions are proteinaceous infectious particles, ...