“In producing any viral vector, the transfection reagent needs to guarantee both high titre and infectivity, as well as quality, to satisfy the needs of a particular disease indication,” says Deb.

Maximizing production of safe and effective viral vectors is essential to match this growing need. In this talk, we present optimization strategies for the transfection step of vector production to ...

They engineered an adenoviral vector to include a repressor protein ... By leveraging the advantages of a transfection-free helper system while sidestepping the downsides, rAAV manufacturing ...

Ad5-CMV-eGFP virus is a powerful tool for determining the transfection efficiency of an Ad5 virus in ... the eGFP expression will be slightly less than seen in the Ad5-CMV-eGFP vector. Ad5-CMV-Empty ...

The move aims to enhance Merck’s capabilities in viral vector manufacturing for cell and gene therapies. MilliporeSigma specialises in developing and commercialising transfection re-agents known ...

First generation vectors may be suitable for applications where transient, high level activity is sufficient, and where immune responses to the vector or transgene are ... the adenovirus backbone ...

non-viral transfection for cell therapy Information you provide will be shared with the sponsors for this content. Technology Networks or its sponsors may contact you to offer you content or products ...

The Baculovirus Expression Vector System is a versatile platform ... that enables high-yield production of proteins and viral particles at small and large scales. The system includes an improved ...