Cystic fibrosis (CF) pulmonary disease is characterized ... Chronic use of aerosolized antibiotics such as tobramycin or colistin, as well as oral azithromycin for its immunomodulatory effects ...

DOI: 10.1016/j.ijpharm.2023.122927 Chelsea R. Thorn et al, Tobramycin Liquid Crystal Nanoparticles Eradicate Cystic Fibrosis‐Related Pseudomonas aeruginosa Biofilms, Small (2021). DOI ...

Tobi (tobramycin) is a prescription drug used to help manage a bacterial infection caused by Pseudomonas aeruginosa in adults and children ages 6 years and older with cystic fibrosis. It’s ...

However, until this year, the only FDA-approved treatment option was tobramycin solution for inhalation (TSI). The US Cystic Fibrosis Foundation currently recommends TSI every other month for ...

Tobramycin sulfate 10mg/mL ... Usual duration: 7–10 days. Severe cystic fibrosis: initially 10mg/kg/day in 4 divided doses; adjust dose based on serum levels. Renal impairment: reduce dose ...