为了深入探究这些突变的功能多样性,1月7日Nature Genetics的研究报道“Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations”,利用CRISPR基因 ...
Verywell Health on MSN1 年
The TP53 Gene and Its Role in Cancer
What is TP53 and what role does it play in cancer? Medically reviewed by Marla Anderson, MD. The TP53 gene is a gene that is ...
Spatially resolved protein profiling in pancreatic adenosquamous carcinoma. Age, number of genomic alterations (GA) per tumor, and alteration frequency of select commonly altered genes based on TP53 ...
在此基础上,该合作团队于近日在Advanced Science杂志上发表题为“MGAT4A/Galectin9-driven N-glycosylation aberration as a promoting mechanism for ...
Study examines the effect of TP53 mutations on outcomes in MDS patients receiving haploidentical haematopoietic stem cell ...
A study released by the National Cancer Center Japan has revealed higher rates of mutations in a tumor-suppressing gene, TP53, in Japanese cancer patients compared to those in the United States ...
Brukinsa had a lower risk of disease progression or death versus Imbruvica, as well as a more favorable safety profile, in R/R CLL and SLL.