T cells and B cells are crucial components of the immune system, working together to mount effective responses against pathogens. However, their interactions can also lead to autoimmune diseases ...
A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.
Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders – T cells – lose their ability to function effectively.