Seizures may occur, usually late in the course. Cognitive decline/dementia is of subcortical vascular type with impaired executive and organizing functions, general mental and psychomotor slowing ...

Unexpectedly, however, the number of microvascular infarcts increased in subcortical structures in dementia patients whose diabetes was treated compared with untreated controls. Conversely ...

is the most common hereditary subcortical vascular dementia. It is caused by the defective NOTCH3 gene, which encodes a transmembrane receptor; over 170 different mutations are known. The main ...

Another thing to notice is general attitude. “Someone affected by subcortical vascular dementia will seem to lose the will to do the things they used to. It’s not so much that the person isn ...