When the essentially healthy pregnant woman presents with severe lower extremity and/or labial edema, the etiology should be explored by thorough history and physical examination (H&P).

The swelling is usually painless ... Testicular torsion usually presents with the sudden onset of severe scrotal pain, in contrast to AISE, which can be moderately painful but is often painless.

"We know that faricimab works well in nAMD and macular edema, and that it is safe according ... that were switched to faricimab and developed severe intraocular inflammation.