The term 'autophagy' was chosen to distinguish the ... and the adaptor or scaffold protein Atg11 to allow selective cargo recognition and packaging. The completed vesicle fuses with the vacuole ...

The researchers further showed that even in selective autophagy, in which extra caution is secured by the proteins that pick ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...

Weak molecular interactions essential for autophagy to begin In order for the degradation of cellular components through autophagy to occur, they must first be recognised as waste. This is done by ...