Thomas Ostwald and David MacLennan were characterizing proteins that bind to calcium in the sarcoplasmic reticulum — a specialized type of endoplasmic reticulum found in muscle cells.

Access to the calcium sites from the other side of the membrane (lumenal side of the isolated sarcoplasmic reticulum vesicles) is expected from kinetic studies to be blocked in the ...

Regulation of sarcoplasmic reticulum calcium release in heart failure It is well established that altered sarcoplasmic reticulum (SR) Ca handling plays a key role in heart failure (HF) pathogenesis.

Sarcolipin (sln) and Sarcoplasmic Reticulum calcium ATPase pump (serca1) expression increase in Japanese medaka (Oryzias latipes) skeletal muscle tissue following cold challenge. Daily thermal ...

Previously, my works have demonstrated apoptotic protein HAX-1 form a chaperone complex that regulates sarcoplasmic reticulum (SR) calcium handling. With proteomic and genomic approaches, my lab is ...