The drug's effect on P-glycoprotein and CYP3A4 is opposite that of ritonavir, acting as an inducer of both. When tipranavir is coadministered with ritonavir, the net effect is P-glycoprotein ...

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment ...

Potentiated by CYP3A4 inhibitors (eg, ritonavir, ritonavir/darunavir, ritonavir/fosamprenavir); adjust ketoconazole dose as needed. Separate dosing of acid neutralizing drugs (eg, aluminum ...

ritonavir in this combination serves a different purpose. It inhibits the enzyme that metabolizes nirmatrelvir (CYP3A4). As a result, it slows the breakdown of nirmatrelvir, resulting in higher ...

By contrast, co-administration of metamizole with a potentially 2.9-fold hepatocytic CYP3A4 induction may result in a reduction or loss of nirmatrelvir/ritonavir effectiveness. 3. Accurate dose ...

Norgestimate 0.18mg, ethinyl estradiol 35mcg (7 tabs); norgestimate 0.215mg, ethinyl estradiol 35mcg (7 tabs); norgestimate 0.25mg, ethinyl estradiol 35mcg (7 tabs); inert (7 tabs). High risk of ...