The signaling pathways activated by retinoic acid are mediated by specific receptors known as retinoic acid receptors (RARs) and retinoid X receptors (RXRs). These receptors form heterodimers that ...

Mark Leid (Oregon State University, Corvallis): "The diverse effects of retinoic acid (RA) on development, cellular growth and differentiation, and homeostasis are mediated by two families of RA ...

“This award recognizes the innovative preclinical work that Orphagen has done to characterize retinoic acid receptor alpha (RARα) as a target for inhibiting autoimmune inflammation of the ...