This could explain how in the presence of Leu-Enk, naloxone detects a reduced number of receptors. However a two-site model is equally able to explain these results. In this model, delta and mu ...
“G-protein coupled receptors, normally, can be activated by specific small molecules that bind in a pocket in the receptor,” explained Nicholas Kalogriopoulos, a postdoctoral fellow in the Ting lab ...
can be activated by specific small molecules that bind in a pocket in the receptor," explained Nicholas Kalogriopoulos, a postdoctoral fellow in the Ting lab and co-lead author of the paper.