In their normal state, genes that code for the normal proteins controlling these critical processes are called proto-oncogenes. However, once they are altered (see below) to become oncogenes ...

Preclinical analysis and clinical validation to identify biomarkers for trifluridine/tipiracil (FTD/TPI) efficacy with or without bevacizumab in patients with metastatic colorectal cancer. This is an ...

Can tumor suppressor genes and proto-oncogenes provide clues on how to stop this process? Aa Aa Aa According to the American Cancer Society, an estimated 294,120 men and 271,510 women will die of ...

What is TP53 and what role does it play in cancer? Medically reviewed by Marla Anderson, MD. The TP53 gene is a gene that is ...

Structural alterations of the genome are commonly observed in human cancer and can contribute to tumorigenesis through a variety of mechanisms including the formation of fusion oncoprotein and changes ...