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腾讯网
17 小时
Cell | 单胚胎蛋白质组学突破——助力不孕不育诊断与个性化治疗
引言我们生命的起点,始于精子与卵子结合形成受精卵(zygote),随后在短短几天内经历一系列精密调控的分裂与分化,最终发展成具有多种细胞类型的囊胚(blastocyst),为胚胎成功植入子宫做好准备。然而,即便在最理想的生殖条件下,仍有大量受精卵无法 ...
腾讯网
12 天
Nature Methods | Chip-Tip技术:突破单细胞蛋白质组学研究瓶颈的革命性进展
Ye Z, Sabatier P, van der Hoeven L, Lechner MY, Phlairaharn T, Guzman UH, Liu Z, Huang H, Huang M, Li X, Hartlmayr D, ...
生物通
6 天
赵方庆团队建立人工智能驱动的空间蛋白质组学新技术
近年来,空间组学技术已成为解析组织异质性和复杂细胞相互作用的重要工具。尤其是空间转录组学,在胚胎发育、神经科学和疾病机制研究中展现了巨大潜力。然而,作为直接执行生物功能的核心分子,蛋白质的空间分布研究在技术上面临诸多挑战。现有空间蛋白质组学技术受限于 ...
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