In 1961 the structure of one protein, myoglobin ... It proved difficult to decide by refolding experiments whether or not proline isomerization explains the two unfolded forms of RNase A because ...

This problem will be approached similarly to what I did for studying ZF protein – DNA specificity and my experience with structure analysis of proline-rich protein motifs should also help here.

A protein's function directly depends on its folded structure. Additionally ... which is rich in the amino acid proline. This domain contains a binding site with a high affinity for calcium ...

Incorporating the amino acid building block proline into the nascent protein molecule presents a particular challenge for the cell during protein biosynthesis. Due to its rigid structure ...