Prokaryotic ubiquitin-like proteins (Pups) play a crucial role in the proteasomal degradation system of mycobacteria, particularly in the pathogenic species Mycobacterium tuberculosis (Mtb).

A primary degradation signal (degron) of a short-lived protein is a feature of that ... Remarkably, most prokaryotes, including Escherichia coli, get by without the ubiquitin system.

Comparing protein synthesis in prokaryotic vs. eukaryotic cells is ... It protects the mRNA from degradation by cellular enzymes and aids in the initiation of translation. The poly-A tail, a ...