Results described in the paper more generally suggest that the molecular mechanism of programmed cell death has been conserved evolutionarily from worms to mammals. "Concerning evolutionary ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

A phase 3 clinical trial has shown that adding a targeted immunotherapy drug to chemotherapy dramatically improved – almost ...

Researchers identified two anoikis-related genes linked with CTEPH, and that may serve as diagnostic biomarkers or treatment ...

A group of Penn scientists has developed a new method to remotely control engineered cells inside the human body using heat.

Tislelizumab is BeiGene’s programmed cell death protein 1 (PD-1) checkpoint inhibitor and Anktiva is an interleukin-15 (IL-15 ...

A drug could induce programmed cell death in senescent cells expressing SASP factors. News organizations may use or redistribute this image, with proper attribution, as part of news coverage of this ...

The addition of sintilimab to neoadjuvant chemoradiotherapy achieved a 60% pathological complete response rate vs 47.3% with ...