There are several programmed cell death pathways that lead to cellular self-destruction, either for developmental processes, tissue maintenance, or stress responses. These include apoptosis, ...

"There were a number of papers that had suggested a relationship between cell death and oncogenesis, but it was this tie between ced-9 and bcl-2 that really put the nail in the coffin," comments ...

Immunologic checkpoint blockade with antibodies against the programmed cell death protein-1 (PD-1) or its ligand (PD-L1) is an effective method for reversing cancer immunosuppression and thereby ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological ...

The study is published in Analytical Chemistry. Programmed cell death protein 1 (PD-1) is an important immunosuppressive molecule in the human immune system, and programmed cell death ligand 1 (PD ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

and instead begins a programmed cell death, also known as apoptosis," explains biomedical scientist Nazim Nassar from CDU.

A new study, co-led by a researcher from the Champalimaud Foundation, points the way to potential therapies to prevent the ...

Aligos Therapeutics Inc. has disclosed programmed cell death 1 (PDCD1; PD-1; CD279) and/or PD-1 ligand 1 (PD-L1; CD274) and/or PD-1/PD-L1 interaction inhibitors reported to be useful for the treatment ...

A group of Penn scientists has developed a new method to remotely control engineered cells inside the human body using heat.

Tislelizumab is BeiGene’s programmed cell death protein 1 (PD-1) checkpoint inhibitor and Anktiva is an interleukin-15 (IL-15 ...