is set for 8:15 p.m. ET. The 49ers are three-point favorites in the latest Rams vs. 49ers odds, while the over-under for total points scored is 49. The 49ers are -150 money-line favorites ...

The largest point spread in Super Bowl history was in Super Bowl XXIX in 1995. The San Francisco 49ers entered the game as massive 18.5-point favorites over the San Diego Chargers. Incredibly ...

If the deal goes through, the Los Angeles Rams arch rival San Francisco 49ers could have their early offseason plans derailed. It was expected that if Saleh did not receive a head coaching job ...