Step aside sound barrier: Chemical engineers at Johns Hopkins University have broken the mucus barrier, a long-standing adversary to drug delivery in diseases such as cystic fibrosis, lung cancer, and ...

These changes lead to frequent inflammation and are not affected by drugs targeting the altered mucus production. Cystic fibrosis is caused by hereditary genetic mutations that impair or halt the ...

Understanding the pathophysiology of mucus can inform the development of therapies aimed at improving mucus hydration and clearance, which is vital for managing CF symptoms[4]. Cystic Fibrosis (CF ...

Cystic fibrosis medicines that help to break down mucus in the lungs may carry an unexpected long-term benefit, a study suggests. Cystic fibrosis medicines that help to break down mucus in the ...

Sharma J, et al: A novel G542X CFTR rat model of cystic fibrosis is sensitive to nonsense mediated decay. Birket SE, et al: Ivacaftor reverses airway mucus abnormalities in a rat model harboring a ...

Cystic fibrosis is an invisible disease, it affects lungs and other parts of my body. The big thing it’s the mucus or “frogs” that I have to get rid of. So mucus it’s sort of a sticky ...

Cystic fibrosis is an inherited condition in which the lungs and digestive system can become clogged with thick, sticky mucus. It can cause problems with breathing and digestion from a young age.

The finding could be particularly important to the study and treatment of diseases such as cystic fibrosis, in which the mucus that lines ... and holds them in place. In physics, such an ...

In December, the FDA approved Vertex’s vanzacaftor, tezacaftor and deutivacaftor (Alyftrek) for the treatment of cystic fibrosis in patients ... it causes the buildup of mucus, chronic lung ...

The symptoms of cystic fibrosis usually start in early childhood. Treatments help remove the mucus and reduce infection, but there is currently no cure. People with cystic fibrosis have a shorter ...