leading to stimulation of PKB/Akt and phosphorylation of BAD on serine 136. Whether or not these two opposing mechanisms could act in the same cell at the same time is unclear. The large number of ...

The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...