Dysregulation of phosphorylation and dephosphorylation events is associated with several diseases and malignancies in humans. The determinants of specificity for kinases are not well understood ...

in part through the dephosphorylation of Cdk regulators. Therefore, much remains to be learned about the phosphatases that govern the phosphorylation states of Cdk substrates during late mitosis ...

Focusing on PKA and dephosphorylation enzymes ... Recent research has observed that chemical modifications called phosphorylation of proteins in brain neurons dynamically regulate sleep and ...