This is the GLORYx program. GLORYx predicts phase I and phase II metabolites for the chemical compound(s) provided by the user. The method is based on site of metabolism (SoM) prediction combined with ...

In this context, previous studies demonstrated that non steroidal anti-inflammatory drugs, like diclofenac and ibuprofen, decrease the enzymatic activity of the most important UGTs involved in the ...

Semeta enables more precise metabolite prediction across the key enzymes involved in human Phase I and II metabolism. It also includes models for rat, mouse, and dog cytochrome P450 (CYP), the ...