Stop the Spread. Injecting saline into mouse kidneys did not affect the left or right substantia nigra (top). Injecting fibrils of α-synuclein ablated about half of the dopaminergic neurons (middle ...

A major research breakthrough on Parkinson's disease revealed that an already FDA-approved cancer drug could help stem the ...

The assay for a particular abnormal form of the protein alpha-synuclein – known as αSyn-SAA – could also be used to diagnose people with Parkinson’s more quickly, help identify the best ...

Parkinson's symptoms mainly result from the death or impairment of dopamine-producing neurons in the brain's substantia nigra ...

Stimulating dopamine-producing brain cells wirelessly with gold nanoparticles has proven effective at treating mice with ...

A novel wireless photothermal DBS nanosystem uses nanoparticles to target and restore damaged neurons in Parkinson’s disease, ...

The major mechanism behind Parkinson’s disease is well established – a toxic form of a protein called alpha-synuclein that accumulates inside neurons in clusters, eventually driving cell death ...

A video explainer of Parkinson's disease ... "Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice." ...

Standard indirect immunoperoxidase protocols were applied using antibodies against olfactory markers and α-synuclein ... More than 96% of patients with Parkinson's disease (PD) present with ...