The identification of chemosensory mechanisms that shape the interaction between parasitic nematodes and their ... target the CO 2-sensing pathway. For example, drugs that block GCY-9 function ...

Globally, over 600 million people are infected with the skin-penetrating threadworm, Strongyloides stercoralis, mostly in tropical and subtropical regions with poor sanitation infrastructure.

Drug treatments for filariasis have not changed significantly in over 20 years... Nematode parasitism, both plant and animal, is thought to have evolved independently from free-living groups.