Trouble sleeping is common in other neurodegenerative diseases, but past research has only suggested that it occurs in ...

Such neurons - for example orexin/hypocretin neurons - are increasingly implicated in disorders of energy balance, sleep, motor control, mood, and cognition. SELECTED RECENT PUBLICATIONS: Tesmer AL, ...

In a recent study published in the journal Nature Neuroscience, researchers investigate the role of hypocretin/orexin neurons (HONs) in temptation-resistant voluntary exercise (TRVE). Study ...

There seems to be a loss of orexin producing neurons in the brains of people with narcolepsy, suggesting agonists could strike at the underlying pathology of the condition. Orexin antagonists ...

Jim Fadel at the University of South Carolina Medical School, we are testing the role of the orexin system in attention. The orexinergic system originates within the hypothalamus and projects to ...