ranging from DNA replication to chromatin remodelling. Fuelled by the binding and hydrolysis of nucleoside triphosphates, helicases move along nucleic acid filaments and separate double-stranded ...

Cytarabine is a pyrimidine nucleoside analog used to treat acute myeloid leukemia (AML) and non-Hodgkin's lymphoma. It interferes with DNA synthesis by incorporating into the growing DNA strand, ...

Several antiviral and anticancer drugs target the incorporation of adenine into DNA or RNA. For example, some nucleoside analog drugs, such as vidarabine and fludarabine, mimic adenine and interfere ...