Notch signaling is a crucial cell communication pathway that influences various biological processes, including cell differentiation, development, and tissue homeostasis. This signaling pathway is ...

The data also revealed an association between age-related bone degeneration and a significant upregulation of Notch signaling genes, suggesting that this pathway becomes abnormally active in SSPC as ...

Specifically, we would like to understand how these glycosyltransferases regulate the activity of the Notch signaling pathway in a dosage-sensitive and tissue-specific manner. We have reported a mouse ...