In a model of DYT11 dystonia, heterozygous knock-out mice lack expression of ε-sarcoglycan and have myoclonus, hyperactivity in open-field testing, deficits in beam walking, impaired motor ...

Myoclonus can be classified according to the physical activity with which myoclonic jerks are associated. Glass and colleagues have now proposed the new category of 'orthostatic' myoclonus (in ...