Clearance of driver mutations at day 30 after transplantation was associated with a reduced risk of relapse and better survival among patients with myelofibrosis, a German study showed.

Patients with myelofibrosis who cleared their mutations 30 days following stem cell transplantation experienced fewer relapses. They also achieved longer DFS and OS. Patients with myelofibrosis ...

However, in about half of the cases of primary myelofibrosis, a mutation in the JAK2 gene is found. The JAK2 mutation is also frequently found in those with polycythemia vera and essential ...

particularly the JAK2 V617F mutation, which is commonly associated with other myeloproliferative neoplasms (MPNs) such as essential thrombocythemia and primary myelofibrosis. Recent studies have ...

Myelofibrosis is a rare cancer that affects your bone marrow, the spongy tissue inside some of your bones. In a healthy person, stem cells in the bone marrow make the red blood cells, white blood ...