Although the exact prevalence of Cornelia de Lange syndrome is unknown, it is estimated that the disorder affects 1 in every 10,000 to 30,000 newborn children. The features of Cornelia de Lange can be ...

Mutations that affect cohesin genes cause the human developmental disorder Cornelia de Lange syndrome (CdLS). Mouse models of CdLS show placental abnormalities such as increased placental size and ...