My laboratory has been exploring three aspects of the role of adenosine-dopamine receptor interactions in psychostimulant abuse. First, we are interested in how psychostimulants such as cocaine and ...

New research suggests that mood swings in bipolar disorder are regulated by two clocks: the body’s 24-hour circadian rhythm ...

The dependence of METH on the dopamine transport pathways is believed to contribute to the deficits in socio-cognitive function observed in chronic METH users. Overall, the findings suggested that ...

Meth that enters your brain drastically increases your dopamine levels, creating a powerful reward incentive to keep using. However, it can also kill brain cells, causing long-term damage to your ...

Young adults who use methamphetamine could be more prone ... neurotrophic factor (GDNF), a protein that protects and repairs dopamine, an important neurotransmitter, in areas of the brain related ...

ADHD medications like Adderall and Ritalin, as well as addictive drugs like cocaine and methamphetamine, target the dopamine system, implicating it in habit formation, craving, and euphoria.

Both amphetamine and methamphetamine act directly on the mesolimbic dopaminergic "reward system" [3] by inducing release of dopamine, and to some extent norepinephrine, in the synaptic clefts of ...

We are currently exploring how self-administration of drugs of abuse, such as cocaine and methamphetamine, alter the reactivity of microglia and how ... For example, cocaine exposure causes dual ...