Intestinal metaplasia (IM) occurs when the body replaces the cells that line the upper digestive tract (including the stomach and esophagus) with cells that line the intestines. When IM happens in ...

Willet SG, Thanintorn N, McNeill H, Huh SH, Ornitz DM, Huh WJ, Hoft SG, DiPaolo RJ, Mills JC. SOX9 governs gastric mucous neck cell identity and is required for injury-induced metaplasia. Cell Mol ...

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.

resulting in activated cells, increase in large proteoglycans and a breakdown of the collagen structure. Within these pathological changes, there are areas of fibrocartilaginous metaplasia, and ...