Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...

在医学领域，颅内肿瘤的种类繁多，而其中有一种罕见的肿瘤——颅内间叶性肿瘤（Intracranial Mesenchymal Tumor，IMT），伴随FET-CREB基因融合，这一新型病变现已被纳入2021年版WHO中枢神经系统肿瘤分类。 本案例涉及一名53岁男性患者，体检过程中偶然发现右侧小脑有占位性病变，已持续8个多月但并未出现头晕、头痛等常见症状。通过CT和平扫，发现该区域有一不均匀的稍高密 ...

An international research team led by a Boston College professor has uncovered a drug and diet pairing that could fight a deadly brain cancer The international team combined a calorie-restricted diet ...

The epithelial–mesenchymal transition (EMT) is a cellular transdifferentiation program that enables epithelial cancer cells to acquire traits of high-grade malignancy, notably invasive and ...

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and ...

Mesenchymal-epithelial transition factor (MET) plays a relevant role in growth, survival, migration and tissue repair. Alterations in MET have been found in non-small-cell lung cancer and head and ...

This cohort included 91 patients (younger than 18 years) from two clinical trials: infantile fibrosarcoma (49), other soft tissue sarcomas or related mesenchymal tumors (41), and bone sarcoma (1).

Composition of the tumor microenvironment. Tumor tissue contains a heterogenous population of cells of epithelial and mesenchymal origin and also immune cells embedded in a protein-rich ...

Pancreatic cancer cells can be roughly divided into two main subtypes: epithelial and mesenchymal, based on their appearance and their molecular profile. "However, the tumor cells can change their ...

Dr. Jerome Zeldis and Dr. Blythe Sather bring exceptional backgrounds in cell therapy and solid tumorsCAMBRIDGE, Mass., Jan.