Sickle-cell disease, usually presenting in childhood, occurs more commonly in people (or their descendants) from parts of tropical and sub-tropical regions where malaria is or was common.

Base editing utilizes enzymes to modify single amino acids at the most foundational unit of DNA, called a base.

The R21/Matrix-M malaria vaccine offers the highest efficacy in the history of malaria vaccine development as reported by Mehreen Datoo and colleagues.1 The potential for saving the lives of African ...

The American Red Cross explains that sickle cell disease likely originated in Africa thousands of years ago as a defense against malaria. One of the many serious symptoms of sickle cell disease is ...

We thank the authors for their interest in our paper, and their queries. In response to Yue Li and Guangsen Liu, given the current situation of malaria deaths and cases increasing in recent years,1 it ...

January 31, 2025 expert reaction to NICE final draft guidance on exagamglogene autotemcel (exa-cel) for severe sickle cell disease . Scientists comment on final draft guidance fro ...

However, carriers can have children who inherit sickle cell disease and may exhibit symptoms. Therefore, unless you conduct DNA paternity tests that confirm the child is not yours, the fact that ...

Scientists at UCL examined DNA from human's closest relative chimpanzees to make a significant finding in relation to how their bodies have adapted to resist the ravages of malaria - one of the world' ...

Dr. Remy is an international expert in adult and pediatric sepsis, COVID-19 disease, and global health. As an adult and pediatric critical care physician, his research focuses on heme-based ...