The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
Armed robbery in Revesby4 天
Spliceosome: Cells' Error-Free MRNA Production Explained
A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...
Nature11 个月
Intron recognition comes of AGe
The vast majority of introns are removed by the major spliceosome, a 60 S complex containing five small nuclear RNAs (snRNAs: U1, U2, U4, U5 and U6) and well over 50 different polypeptides (Fig.
AZoLifeSciences on MSN1 天
High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes
A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into ...
idw4 天
Spliceosome: How Cells Avoid Errors When Manufacturing mRNA
“However, analyzing the components flexibly bound to the periphery of the spliceosome was a major challenge for our work,” explains Dr Komal Soni from the BZH. Based on this structural ...
来自MSN2 个月
Slow editing of protein blueprints leads to cell death, spliceosome study discovers
During splicing, this transcript undergoes modification: a cellular editing complex, the spliceosome, removes certain segments. The outcome varies depending on which parts are cut out, resulting ...