Little did we know that MYC would be multifunctional and achieve its notoriety as a potent oncogene by regulating many pathways that collectively contribute to neoplasia. A brief overview of the ...

This is a very powerful oncogenic pathway set off by MYC activation. We need to understand this complex cascade of events in detail to find out more effective ways to manage the disease." ...

The Myc family of transcription factors ... of other cancer types due to their potential in targeting key oncogenic pathways. Thus, the exploration of synergistic combination therapies ...

Our laboratory studies oncogene and tumor suppressor induced cancer-specific cellular programs, which cause therapeutic vulnerabilities in breast cancer. Our current research specifically focuses on ...

The MYC family of proteins ... a spectrum of other cancer types due to their potential in targeting key oncogenic pathways. Thus, the exploration of synergistic combination therapies, encompassing ...

Pathway-specific Expression Analyses Indicate Tumor Behavior and May Serve as a Guide to Targeted Treatment Defining oncogenic pathway signatures in neuroblastoma will assist in outcome prediction ...

which has a mutation in the Myc oncogene. These mice have a long delay before tumors develop, giving researchers a chance to observe what happens early on in cancer. Because B-cell lymphoma ...