Extranodal non-Hodgkin lymphoma (NHL) makes up over one-third of NHL cases, yet remains understudied and in need of deeper ...

"One of the things that struck us when we looked at these tumors was that patients who were responding to immunotherapy had tertiary lymphoid structures," he says. Like lymph nodes, the structures ...

TLSs pop up in many tissues, including most tumors, where they have been associated ... unusual type of immune cell called group 2 innate lymphoid cells (ILC2s) might have anti-cancer effects ...

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign ...

Vinod Balachandran identified the molecular pathway involved in the formation of tertiary lymphoid structures ... including tumors, to bolster the local immune response. Understanding the ...

This stimulated TLSs to form in pancreatic tumors. The team went on to show ... IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer, Nature (2025).

Lymphoid stem cells become different types ... for 5 years after diagnosis as someone without CML. Myeloproliferative neoplasms are a group of cancers that cause the overproduction of cells ...

for lymphoid neoplasms and blood stem cell transplant for hematologic malignancies. His goal is to identify the best treatment sequence or combination for patients with high-risk lymphoma and CLL.