Discover how tirzepatide, a diabetes drug, offers hope for congenital generalized lipodystrophy (CGL) treatment, potentially ...

Reiko Hanada; Hitoshi Teranishi; James Todd Pearson; Mamoru Kurokawa; Hiroshi Hosoda; Nobuhiro Fukushima; Yoshihiko Fukue; Ryota Serino; Hiroaki Fujihara; Yoichi Ueta ...

A diabetes drug may beat costly shots for patients with a rare genetic condition, according to a Rutgers Health study.

The Nmu gene was targeted for deletion by standard techniques (Supplementary Fig. 1 online). Nmu-/-mice were generated on a BL6/129 mixed background and backcrossed four times into C57BL/6J mice.

The hypothalamus sits at the crossroads of nutritional signal input and feeding behavior output. This part of the brain can take signals from hormones such as leptin and translate them into ...

A weekly injection of diabetes medication could replace painful daily hormone shots for patients with a rare form of lipodystrophy.

Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting ... genetic and metabolic pathways. And the study of adipose or fatty ...