and reduced left ventricular ejection fraction (LVEF). The substantial proportion of HF patients who have preserved systolic function (PSF) and an LVEF of 40–50% or more are rarely included in ...
Cumberland Pharmaceuticals’ Duchenne muscular dystrophy (DMD) drug has improved the amount of blood pumped by the heart, ...
There is an unmet need for therapies targeting Duchenne muscular dystrophy (DMD)–related heart disease, and phase 2 results ...
In mild (grade I) aortic regurgitation ... may be mild-to-moderate (LVEF 40% to 55%) or severe left ventricular dysfunction (LVEF < 40%). (Otto CM, et al. Circulation. 2020;34A[e105, table ...
In the first 22 months of a mavacamten REMS program, few patients needed a temporary interruption in treatment for LVEF below 50%.
A failing left ventricle cannot accommodate the increased ... persistent orthopnea was associated with failure of improvement of LVEF and increased risk of hospitalization. We have shown that ...
Bayer announced the submission of a marketing authorization application to the European Medicines Agency (EMA), seeking approval in the EU for the use of finerenone in adult patients with HF with a ...
In mild (grade I) MR, RVol is less than 30 mL ... subdivided into Stage C1 (characterized by a left ventricular ejection fraction [LVEF] above 60% and a left ventricular end-systolic dimension ...
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