In this article, we will discuss what is meant by drug metabolism and pharmacokinetics (DMPK) and explore its role in various stages of pharmaceutical development. As biology presents ever-more ...

As biology presents ever-more challenging targets, those in the drug discovery field are pushing ahead with new tools to design or discover drugs that have optimal kinetics. But how familiar are you ...

The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

We're kicking things off with a bang in 2016! Join us as Robert Copeland starts things off with a look at the importance of target conformational dynamics and its impact on drug affinity. The ...

Pharmacokinetics is an area of pharmacology concerned with the time course of absorption, distribution, metabolism and excretion (collectively ADME) of drugs from biological systems in order to ...

The purpose of this study was to evaluate the pharmacokinetics of intranasal ... route potentially improves systemic bioavailability of drugs since it bypasses gastrointestinal degradation and ...