Thus, neuronal insulin-like signaling appears to be a key regulator of various essential functions in C. elegans, and the metabolic and reproductive defects induced by whole-body deletion of DAF-2 ...

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Other signaling molecules must move much farther ... Dopamine receptors bind dopamine, insulin receptors bind insulin, nerve growth factor receptors bind nerve growth factor, and so on.

Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...

In Alzheimer’s, there is much lower brain glucose uptake and metabolism coupled with a decrease in insulin signaling and receptor activity compared to age-matched healthy aged adults.

In the case of mitochondrial recycling, this works as follows: If sufficient energy is available, a signal is transmitted ...