Mitochondrial fusion is the physical merging of the outer and then the inner mitochondrial membranes of two originally distinct mitochondria. Mitochondrial division is the breaking apart of one ...

Mitochondrial dysfunction has long been associated with aging, making preventing or reversing the organelle’s decay a high priority for longevity researchers. One key target for such work is the ...

a protein complex found within the inner mitochondrial membrane that the Chandel laboratory previously demonstrated supports other immune responses. Whether the mitochondrial respiratory chain is ...

A novel mechanism that enables cells to maintain energy production even when their main power supply drops/fails has been uncovered by biologists at Duke-NUS Medical School. In collaboration with an ...

Elamipretide is a cell-permeable peptide compound designed to improve mitochondrial function by targeting the inner mitochondrial membrane where it binds reversibly to cardiolipin. We continue to work ...