Three-dimensional (3D) cell culture is an attractive alternative to animal model research, and it is a predictive method for drug discovery and compound screening. By incorporating extracellular ...

AMSBIO has launched MatriMix for PDX, a fully defined extracellular matrix (ECM) hydrogel comprising of collagen ... MatriMix for PDX is a ready-to-use 3D culture substrate product optimized for ...

“In this work, we demonstrate for the first time that a combined therapy of a systemically delivered drug and local injection of our hydrogel delivers a rapid increase in bone density, and could ...

A new injectable hydrogel, however, is claimed to drastically ... between a person's osteoblasts – which are bone-building cells – and their osteoclasts, which are bone-degrading cells.

“In this work, we demonstrate for the first time that a combined therapy of a systemically delivered drug and local injection of our hydrogel delivers a rapid increase in bone density, and could ...

ensuring it stays localized at the injection site. It responds to elevated glutathione (GSH) levels, a molecule abundant in tumour cells. Upon encountering high GSH levels, the hydrogel triggers a ...

Based in fundamental materials science, the group synthesizes cytocompatible and cell-instructive biomaterials ... Recent applications of work from the group include: (i) injectable hydrogels to treat ...

When combined with a popular anti-catabolic drug Zoledronate, injection site bone density increased as much as 4.8-fold in only 2-4 weeks. The hydrogel injections are not a cure-all, and did not ...

The hydrogel, composed of ultra-short peptides – biocompatible and biodegradable building blocks of proteins – is designed to remain insoluble in biological fluids, ensuring it stays localised at the ...

The Indian Institute of Technology (IIT) Guwahati, in collaboration with Bose Institute, Kolkata, has developed an advanced injectable ... cells, leading to debilitating side effects. “Our ...