In the case of inducible systems ... two basic aspects of conditional gene targeting using Cre-mediated recombination, namely the fidelity of Cre expression from a given Cre transgene and the ...

It seems that proteins called hypoxia-inducible factors (HIFs) can affect gene expression in low-oxygen conditions. While some control of gene expression is mediated through control of whether a ...

Researchers at Cellectis leveraged gene editing to create a CAR T cell that acts in an IF/THEN system. Traditional methods to develop CAR T cells that use the patient’s cells introduce challenges ...