A new type of cancer drug might help treat brain diseases like Alzheimer's, mouse studies suggest. The drugs block an enzyme called indoleamine-2,3-dioxygenase 1 (IDO1), researchers reported.
In particular, higher levels of an enzyme called indoleamine-2,3,-dioxygenase 1 (IDO1) have been reported ... is disrupted in several different neurodegenerative disorders, this treatment strategy ...
PD-L1 is a cell surface receptor expressed on both tumour and regulatory immune cells and functions as a checkpoint to inhibit T-cell function, while IDO1 is an enzyme involved in T-cell ...