The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...

Although this hypothesis is attractive in its simplicity with respect to the propagation of histone PTMs, it is difficult to conceive of how each H3–H4 dimer or tetramer would be deposited after ...

Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional ...

Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society by ...