This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

"In our laboratory models, in our mouse models, the mice were cured ... Initially, the trial will recruit patients with HER2-driven tumors expressing the p95HER2 protein who have exhausted ...

A team led by the Institute for Bioengineering of Catalonia (IBEC) and the Hospital del Mar Research Institute has developed ...

In response, the Genentech team grafted the mouse antibody onto a human ... It was a promising treatment for HER2+ metastatic breast cancer, especially for those who had exhausted all other ...

The single center, investigator-initiated, dose escalation trial enrolled 12 patients with HER2-positive Stage IV solid tumor malignancies, including three gastric, one esophageal, four colorectal ...