Aging is inevitable for most cell types in the human body, but hematopoietic stem cells (HSCs) seem to defy the process. They retain their self-renewing ability almost throughout an organism’s ...
Our research will determine how aging of human blood stem cells leads to dramatic increases in disorders of platelets, cells that normally prevent bleeding but form harmful clots when dysregulated. To ...
Nothing lives forever, but compared to other cells in the body, hematopoietic stem cells ... cyclophilin A accelerated natural aging in the stem cell compartment. In contrast, reintroducing ...
Hematopoietic stem cells give rise to all blood cells in the body. Most of the time they are not dividing. Rather, they serve as a reserve for the times when the body needs rapid blood formation. “One ...
Hence, studies on hematopoietic stem cells (HSCs) – self-renewing, multipotent stem cells capable of generating and, thus, replenishing all myeloid and lymphoid lineages – are of utmost importance.
Hematopoietic stem cells (HSCs) are the precursors of all cells of the peripheral blood ... as well as how infections can contribute to aging and oncogenesis.
Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells. This vital function is often disrupted in ...