在乳腺癌的治疗领域,HER2阳性乳腺癌一直是研究的重点。近期的研究揭示了HER2的不同免疫组化(IHC)状态与病理学完全缓解(pCR)之间存在显著关联。这不仅对医生在治疗方案选择上的指导意义,更为广大乳腺癌患者带来了新的希望。 乳腺癌是全球女性中最 ...
在乳腺癌的治疗领域,HER2状态的影响逐渐受到重视。根据近日发表于医学界的研究,HER2免疫组织化学(IHC)检验结果和病理学完全缓解(pCR)之间存在显著相关性,尤其是在接受抗HER2治疗的患者中,研究结果引发了广泛关注。 研究数据从2021年1月到2022年5月的 ...
Trastuzumab, tested only as a single agent, has been shown to achieve 7% response in heavily pretreated patients with AOC with 3+ and 2+ HER2 immunostaining by immunohistochemistry (IHC).
IHC uses a scoring system of 0 to 3 to designate ... Alternate methods of pathologic assessment and interpretation of HER2 testing are being assessed in an effort to improve accuracy.
Cardoso, Hélder P. Oliveira and Jaime S. Cardoso. Human epidermal growth factor receptor 2 (HER2) evaluation commonly requires immunohistochemistry (IHC) tests on breast cancer tissue, in addition to ...
The analysis was performed on independent study sets of HER2-positive and negative/low breast cancers, already analyzed by central immunohistochemistry (IHC) and FISH testing. Phospho-HER2 and ...
AstraZeneca and Daiichi Sankyo’s Enhertu (trastuzumab deruxtecan) has been approved in the US for the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, ...
The MIST dataset is a staining transformation dataset related to breast cancer diagnosis, containing aligned H&E-IHC images for four crucial biomarkers in breast cancer diagnosis: HER2, Ki67, ER, and ...
A new study has demonstrated the value of Lunit’s AI-powered pathology tools in improving human epidermal growth factor receptor 2 (HER2) biomarker evaluation in metastatic colorectal cancer ...