Trastuzumab, tested only as a single agent, has been shown to achieve 7% response in heavily pretreated patients with AOC with 3+ and 2+ HER2 immunostaining by immunohistochemistry (IHC).
IHC uses a scoring system of 0 to 3 to designate ... Alternate methods of pathologic assessment and interpretation of HER2 testing are being assessed in an effort to improve accuracy.
Cardoso, Hélder P. Oliveira and Jaime S. Cardoso. Human epidermal growth factor receptor 2 (HER2) evaluation commonly requires immunohistochemistry (IHC) tests on breast cancer tissue, in addition to ...
The analysis was performed on independent study sets of HER2-positive and negative/low breast cancers, already analyzed by central immunohistochemistry (IHC) and FISH testing. Phospho-HER2 and ...
AstraZeneca and Daiichi Sankyo’s Enhertu (trastuzumab deruxtecan) has been approved in the US for the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, ...
The MIST dataset is a staining transformation dataset related to breast cancer diagnosis, containing aligned H&E-IHC images for four crucial biomarkers in breast cancer diagnosis: HER2, Ki67, ER, and ...
A new study has demonstrated the value of Lunit’s AI-powered pathology tools in improving human epidermal growth factor receptor 2 (HER2) biomarker evaluation in metastatic colorectal cancer ...